December 5, 2017
Towards a vaccine for Alzheimer's disease
Researchers at Cinvestav in Mexico have produced a promising vaccine candidate against Alzheimer’s disease by targeting the a myloid-beta (Aβ) peptide. The vaccine, created by a team led by Miguel Angel Gómez Lin, used an Aβ epitope – a molecule-specific receptor – that is known to be present in the full-length amyloid-beta peptide, as well as in its truncated version, which is often found in the brains of Alzheimer’s patients. After immunization, Aβ-specific antibodies from the mice were isolated and found to effectively bind to amyloid plaques in both mice and human brains (Inflammopharmacol doi: 10.1007/s10787-017-0408-2). {read more here}