PET study finds higher odds of Alzheimer’s during menopause transition

Using PET imaging with Carbon-11 labeled Pittsburgh Compound B (PiB), which binds to beta-amyloid plaque in the brain,  researchers found a significant increase in amyloid among perimenopausal and menopausal women between the ages of 45 and 60 years.  “Overall, these findings provide a plausible rationale for greater prevalence of Alzheimer’s disease in women due to earlier initiation of pathology during the aging process,” wrote lead author Lisa Mosconi, PhD, from Weill Cornell Medicine and colleagues. The results also “indicate a time frame of the perimenopause-to-menopause transition for early intervention to prevent and delay progression of Alzheimer’s in women.” {read more here}

Researchers studying eating used a newly developed PET scan technique to identify when dopamine is released, as well as the areas of the brain linked to dopamine release. {read more here}

According to meta-analysis results published in NeuroImage: Clinical, [18F]-fluorodeoxyglucose-positron emission tomography (FDG-PET) is a reliable tool for detecting consistent functional brain abnormalities in Parkinson disease when compared with other imaging modalities. {read more here}

PSMA PET/CT detected more lesions in patients with prostate cancer and resulted in more changes in management than CT alone when utilized prior to radiotherapy, reported authors of a Dec.14 study in the Journal of Nuclear Medicine. {read more here}